I'm not sure how you end the game. Once you get the Quinta Essentia (lift curse without any kill effects), and you get it back to the sorceress, what do you do? dropping the item in her space does nothing, as far as I can tell-- the item merely shifts off into another square. Splashing the item results in '(Azhmaya liver with Bictea) effects the dying sorceress!' (in this case the essentia was made via mixing with a fume, improve strength, persistence, persistence herb) with no other effects. The fumes effect you also, of course, which gives you a cautionary message that makes it sound like you weren't simultaneously affecting the sorceress, but there's no message when the sorceress is affected besides the aforementioned one and her timer keeps counting down. I still have the potion even after splashing it, though (double persistance may be part of letting you do that, I thought, but it works even with Lift Curse instead so that's weird) so as long as I drop and pick up the item after each use I can keep filling the area with fumes. Is there an amount of Lift Curse that's needed? I only have it at 1 currently.
I tried getting rid of the Fume effect and it didn't work. Probably should have tried boosting lift curse first because now the essentia is gone :/ 'affects the Dying sorceress' just like always but no victory.